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Table 2 Participant Characteristics at Baseline, Responders v. Non-responders (N = 33)

From: One-year follow-up of B vitamin and Iron status in patients with phenylketonuria provided tetrahydrobiopterin (BH4)

Variable (baseline)

< 18 years

≥18 years

Responder (n = 11)

n (%) or mean (sd)

Non-responder (n = 8)

n (%) or mean (sd)

Responder (n = 7)

n (%) or mean (sd)

Non-responder (n = 7)

n (%) or mean (sd)

Age (years)

9.7 (3.4)

10.4 (4.4)

27.4 (7.6)

34.2 (9.7)

Sex

 Male, n (%)

8 (73)

3 (37)

2 (29)

3 (43)

 Female, n (%)

3 (27)

5 (63)

5 (71)

4 (57)

Average weight (kg)

34.8 (19.2)

46.4 (27. 8)

72.4 (17.2)

76.4 (20.8)

Average height (cm)

138.7 (21.2)

138.4 (23.8)

168.2 (10)

165.3 (7.8)

MF adherence n (%)

 Take full amount

7 (64)

7 (88)

4 (57)

2 (29)

 Do not take full amount

3 (27)

0

2 (29)

3 (43)

 N/A

0

0

1 (14)

0

 Missing

1 (9)

1 (12)

0

2 (29)

Total Calories (kcal)

1556 (321)

1571 (344)

2354 (830)

1812 (275)

Taking two MF

 Yes

2 (18.2)

3 (37.5)

1 (14.3)

2 (28.6)

 No

9 (81.8)

5 (62.5)

6 (85.7)

5 (71.4)

Percent of total protein intake from MFb

54.1 (35.2)a

76.5 (13.8)a

49.3 (29.5)

59.2 (29.1)

  1. N/A not applicable, sd standard deviation
  2. aMean intake of MF in g significantly different between responders/non-responders at baseline for < 18 years (p = 0.02)
  3. bIncludes protein intake from both primary and secondary MF