Table 2 Model estimated number of X-ALD and CCALD cases per year
Sensitivity Analyses | Number of cases | |||
|---|---|---|---|---|
X-ALD Cases | 95% Confidence Interval | CCALD Cases | 95% Confidence Interval | |
Base case | 18.3 | (12.1,26.6) | 9.7 | (5.5,15.3) |
Incidence rate doubled | 36.5 | (24.,53.2) | 19.3 | (11.1,31.0) |
Incidence rate halved | 9.1 | (6.,13.2) | 4.8 | (2.7,7.6) |
CCALD 20% of total X-ALD | – | – | 3.6 | (2.4,5.3) |
CCALD 15% of total X-ALD | – | – | 2.7 | (1.8,4.) |
CCALD 10% of total X-ALD | – | – | 1.8 | (1.2,2.7) |
Both girls and boys screened | 35.6 | (23.7,51.9) | – | – |