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Fig. 6 | Orphanet Journal of Rare Diseases

Fig. 6

From: Adult Niemann-Pick disease type C in France: clinical phenotypes and long-term miglustat treatment effect

Fig. 6

Time-to-severe-event analysis for: a) impaired gait (need for wheelchair), b) manipulation (severe dysmetria); c) speech (non-verbal communication); and d) swallowing (need for gastrostomy) subscores in patients treated with miglustat for > 2 years versus untreated patients and those receiving miglustat for < 2 years. N1, number of patients untreated or receiving miglustat for ≤2 years; N2, number of patients treated with miglustat for > 2 years; y, years

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