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Fig. 3 | Orphanet Journal of Rare Diseases

Fig. 3

From: Molecular and cellular characterizations of human cherubism: disease aggressiveness depends on osteoclast differentiation

Fig. 3

Bone remodeling marker: RANK-L, OPG, RANK, NFATc1 immunohistochemistry. a Case 1-C2 showed that both stromal and MGC cells express RANK in their cytoplasm (black arrow) (scale bar = 50 μm). b Case 1-C1 showed that stromal cells around MGC (black arrow) express OPG (scale bar = 200 μm). c Case 1-C1 mononuclear stromal cells (black arrow) distant from MGC express RANKL (scale bar = 200 μm). d Case 1-C2 showed expression of NFATc1 in MGC nuclei and cytoplasm (scale bar = 100 μm)

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172