Fertility in classical galactosaemia, a study of N-glycan, hormonal and inflammatory gene interactions

Table 3 Serum Leptin levels in CG vs healthy controls and correlations with hormone, G-ratios and ANXAI gene expression

Serum Leptin^a
Gender	Group	n=	Mean ± SD	Range	p-value
Male	CG	18	2.6 ± 1.86	0.10–6.60	0.031
Male	Healthy Control	10	7.40 ± 5.60	0.70–18.80	0.031
Female	CG	19	13.22 ± 9.47	1.18–33.12	0.099
Female	Healthy Control	10	20.10 ± 12.53	3.60–45.44	0.099
Spearman Correlations - Serum Leptin Corrected for BMI^b
Variable 1	Variable 2	Gender	n=	p-value	Correlation Coefficient
Leptin, BMI corrected	G0/G1	Male and Female	26	0.0001	− 0.681
Leptin, BMI corrected	G0/G2	Male and Female	26	0.002	− 0.588
Leptin, BMI corrected	Testosterone	Male	11	0.026	0.664
Leptin, BMI corrected	FSH	Male and Female	25	0.027	0.441
Leptin, BMI corrected	ANXA1	Female	17	0.012	0.593

^aLeptin data was available for 37 of 54 patients. The p-values of this section show results of the difference in means of serum leptin levels in CG vs healthy control (Mann Whitney U test)
^bCorrelations between serum leptin corrected for BMI vs other variables in combined and separate gender cohorts

ISSN: 1750-1172