Table 1 Summary of human cell lines used in the study
From: Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease
Subject | Fibroblast ID (Coriell) | iPSC lines | Gender | Genotype |
|---|---|---|---|---|
WT | GM05659 | HT268A | Male | Wild Type |
Tay-Sachs | GM00221 | HT134A, E | Male | Homozygous-c.1278insTATC on exon 11 of HEXA gene |
Tay-Sachs | GM00515 | HT151A, C | Female | Heterozygous-c.1278insTATC and Trp392Ter, both mutations on exon 11 of HEXA gene |