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Fig. 4 | Orphanet Journal of Rare Diseases

Fig. 4

From: Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease

Fig. 4

Effect of hexosaminidase A (Hex A) on lipid accumulation in TSD NSCs. a Nile Red staining of NSC HT134A and NSC HT151A after 4 h incubation with Hex A. b Normalized percent Nile Red IxA of TSD NSCs after treatment with Hex A. Nile Red IxA values of TSD NSCs treated with HexA were normalized to untreated TSD NSCs as 100% and Nile Red IxA of WT NSCs as 0%. Data are mean ± SEM (n = 30), **** p < 0.0001, compared to each other. IxA, integrated cell intensity

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