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Fig. 1 | Orphanet Journal of Rare Diseases

Fig. 1

From: Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease

Fig. 1

Characterization of Tay-Sachs disease iPSCs and NSCs. a The iPSCs derived from TSD patients and WT control fibroblasts expressed pluripotency protein markers SOX2, Oct4, Nanog, TRA-1-60 and SSEA4. b Flow cytometry analysis of TSD iPSCs, > 94% of iPSCs expressing Nanog and TRA-1-60 markers. c Immunofluorescence staining of TSD and WT NSCs. Nestin, SOX1, and SOX2 are neural stem cell markers while Oct4 is an iPSC marker

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172