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Table 1 The demographics of the patients in the two clinical centers are summarized

From: Annual severity increment score as a tool for stratifying patients with Niemann-Pick disease type C and for recruitment to clinical trials

Centre

Total

Median age (years) by centre at first measurement

Female

Male

Median age (years) at first measurement (female)

Median age (years) at first measurement (male)

Repeat measure median

Range of number of repeat measures

Repeat measures in years (median, min, max)

Patients on miglustat therapy at any point in the study

Patients with seizure recorded on at least one visit

Manchester

13

11.16

8

5

12.77

3.92

5

3–9

4.01, 1.05, 6.36

12 (92%)

5 (38.5%)

Mainz

25

12.45

11

14

11.61

16.76

3

2–7

3.50, 0.94, 5.16

24 (96%)

13 (52.0%)

  1. Age in years at first measurement reflects patient age at the first clinical visit included in this study