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Fig. 1 | Orphanet Journal of Rare Diseases

Fig. 1

From: Annual severity increment score as a tool for stratifying patients with Niemann-Pick disease type C and for recruitment to clinical trials

Fig. 1

Distribution of the study cohort with each patient represented once (first visit) plotting age against unadjusted clinical severity (minus hearing). a Patients fell into six main subgroups defined by lines a-f (latent class mixture regression model). b The same data are presented colour coded to lines a-f with arrows showing progression in severity score from first to last visit for each individual in the study

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