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Fig. 2 | Orphanet Journal of Rare Diseases

Fig. 2

From: Key issues in Rett syndrome: emotional, behavioural and autonomic dysregulation (EBAD) - a target for clinical trials

Fig. 2

Emotional, Behavioural and Autonomic Dysregulation (EBAD) and its clinical presentation in Rett Syndrome. Abbreviations: EBAD (Emotional, Behavioural and Autonomic Dysregulation). Notes: a Stress can cause functional changes in epigenetics and it is highly probable that the epigenetic mechanisms controlled by MeCP2 form a crucial component of the stress response. b Physical problems include seizures, pain and discomfort, and infections

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