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Fig. 2 | Orphanet Journal of Rare Diseases

Fig. 2

From: Molecular diagnosis of anti-laminin 332 (epiligrin) mucous membrane pemphigoid

Fig. 2

Localisation and structure of laminin 332 at the dermo-epidermal junction. a Laminin 332, a major component of the lamina densa, is an extracellular matrix protein binding to collagen XVII/BP180, α6β4 integrin, and collagen VII. b Laminin 332 is a heterotrimer composed of α3, β3, and γ2 chains showing a cross-like structure with a large globular domain at the base of the cross

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