Patient | Nerve conduction | MRI brain (age of study, years) |
---|---|---|
1 | Normal | Normal; hypoplastic optic nerves (2 yrs., 3 yrs) |
2 | N/A | Normal (1.5 yrs) |
3 | Normal | Mild delay in myelination for age; subcortical white matter volume loss, thin corpus callosum (8 mos, 1.3 yrs) |
4 | Normal | Normal |
5 | Normal | Normal; hypoplastic optic nerves |
6 | N/A | N/A |
7 | Normal | Normal |
8 | Normal | N/A (CT brain = mild cerebral atrophy) |
9 | Normal | Hyperintense signal (T2FLAIR) in optic radiations (12 yo) |
10 | Normal | Delayed myelination for age, mild cerebral atrophy, thin corpus callosum (6 yrs) |
11 | N/A | Delayed myelination in temporal lobes (1.8 yrs) |