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Table 1 Frequency of ocular findings in the National EB Registry study population by EB subtype (%)

From: A review of scoring systems for ocular involvement in chronic cutaneous bullous diseases

  EB Simplex Junctional EB Dystrophic EB
Manifestation Localised (N = 1092) G-S (N = 113) G-I (N-96) Ogna (N = 379) G-S (N = 40) G-I (N = 190) DDEB G (N = 424 RDEB G-S (N = 139) RDEB G-I (N = 265) RDEB Inversa (N = 17)
Corneal erosions/blisters 0.92 6.19 3.13 2.64 47.50 25.26 2.12 74.10 32.45 35.29
Corneal scarring 0.27 0.00 3.16 0.53 26.83 13.37 0.95 50.00 16.92 29.41
Symblepharon 0.00 0.00 0.00 0.00 4.76 2.11 0.00 10.07 1.89 11.76
Blepharitis 0.37 0.88 2.08 0.26 7.14 6.32 0.71 17.52 6.46 17.65
Ectropion 0.00 0.00 0.00 0.00 14.29 2.11 0.00 7.19 1.90 0.00
Lacrimal duct obstruction 1.19 2.65 1.04 1.85 2.38 4.23 1.65 5.80 5.30 11.76
Impaired vision 13.17 13.27 15.63 16.14 16.67 13.68 17.18 38.13 21.89 41.18
Blindness 0.82 1.77 0.00 0.53 0.00 1.58 0.94 6.47 1.14 0.00
  1. Abbreviations: G-S = generalised-severe; G-I = generalised-intermediate; G = generalised
  2. Source: Fine JD, Johnson LB, Weiner M, Stein A, Cash S, Deleoz J, et al. Eye involvement in inherited epidermolysis bullosa: experience of the National Epidermolysis Bullosa Registry. Am J Ophthalmol. 2004;138:254–262. (Permission for reuse obtained under RightsLink)