Mineralization of alpha-1-antitrypsin inclusion bodies in Mmalton alpha-1-antitrypsin deficiency

Table 2 Main clinical and laboratory findings in Z AAT patients

Case	Age	Sex	AAT level	Liver histology	Calcification	Genotype
1	22	M	28^a	cirrhosis	–	Homozygous
2	44	M	82^a	cirrhosis	–	Homozygous
3	45	M	75^a	cirrhosis	–	Homozygous
4	56	F	102^a	Cirrhosis and HCC	–	Compound heterozygous (S/Z)
5^c	11	F	125^b	PSC	–	Heterozygous
6^d	17	M	196^b	Mild CAH	–	Heterozygous
7^d	13	M	222^b	NSRH	–	Heterozygous

^aRadial immunodiffusion (n.v. 200–400 mg/dL); ^bNephelometry (n.v.90–200 mg/dL); ^cPSC: Primary sclerosing cholangitis; ^dLiver biopsy obtained during a staging for Hodgkin’s lymphoma; CAH = Chronic Active Hepatitis; NSRH = Non Specific Reactive Hepatitis

ISSN: 1750-1172