Fig. 1From: Improving the analysis of composite endpoints in rare disease trialsStructure of the responder endpoint in rheumatoid arthritis. For the ACR20 endpoint, the continuous ACR-N score is dichotomised at 20% and combined with the rescue medication indicator to form a binary responder index. X1...X8 denotes the disease activity measures which are combined to form the continuous ACR-N scoreBack to article page