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Fig. 1 | Orphanet Journal of Rare Diseases

Fig. 1

From: Status of newborn screening and follow up investigations for Mucopolysaccharidoses I and II in Taiwan

Fig. 1

The algorithm of MPS diagnosis. The suspected cases with reductions in enzyme activity in DBSs detected by tandem mass spectrometry were referred to Mackay Memorial Hospital for further confirmation. The cut-off values were 3.0 μmol/L/h for the initial and second DBS for MPS I. For MPS II, the cut-off values were 6.5 μmol/L/h for the initial and 2.2 μmol/L/h for the second DBS. If the result was far below the cut-off value, the case was highly suspected of having MPS, and the recall process was started by the genetic counselor

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