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Table 4 Estimated prevalence of ACEI-AE in the US, German and French population supported by population-based estimates of the use of ACEI

From: Epidemiology of Bradykinin-mediated angioedema: a systematic investigation of epidemiological studies

 

US (2010/11)

Germany (2011)

France (2006/7)

Description of estimate

%

N

%

N

%

N

Adult population (18+):

 

235,153,929[35]

 

67,085,343 [36]

 

47,911,356 [37]

High blood pressure (18+):

29.1% [19]

68,429,793

31.6% [38]

21,198,968

31.0% [22]

14,852,520

Treated for HBP:

76.4% [19]

52,280,362

71.8% [38]

15,220,859

50.3% [22]

7,470,818

ACEI-use among HBP treated:

33.3% [20]

17,409,361

45.0% [21]

6,849,387

26.7% [39]

1,994,708

Estimated number of patients with ACEI-AE

 (low – 0.12%):

 

20,891

 

8219

 

2394

 (high – 0.30%):

 

52,228

 

20,548

 

5984

Population (all ages):

 

309,349,689[35]

 

80,219,695 [36]

 

61,538,322 [37]

Prev. (# in 10,000) of ACEI-AE in the population:

 low

 

0.7

 

1.0

 

0.4

 high

 

1.7

 

2.6

 

1.0