Gastro-oesophageal reflux - an important causative factor of severe tooth wear in Prader-Willi syndrome?

Table 3 Twenty-four-hour oesophageal acid exposure and manometry findings in 16 adults

Individual	Age (yr)	Sex	Genotype	BMI	Reflux % Pat >4,3%^a	LOS pressure (mmHg)^b	Relaxation pressure (mmHg)^c	UHS mL/min^d	Tooth grinding	Acidic foods and drinks^e
1	38	F	Del	24,2	29	30	Norm	0.17	no	1
2	26	M	Del	33,3	20	N/a	N/a	0.09	yes	1
3	20	F	UPD	41,1	4,8	N/a	N/a	0.05	no	1
4	42	M	Del	38,1	0,2	100	39	0.08	yes	1
5	41	F	Del	44,7	2,4	89	Norm	0.02	no	1
6	35	F	Del	37,6	2,9	84.9	Norm	0.33	no	0
7	25	M	Del	34,9	18	Norm	Norm	0.09	no	1
8	18	F	Del	27,6	6,9	N/a	N/a	0.04	yes	0
9	32	M	UPD	25,1	13,8	Norm	Norm	0.05	yes	1
10	40	F	UPD	23,0	0,8	91	Norm	0.24	yes	1
11	25	F	Del	26,4	9,6	16	Norm	0.16	yes	1
12	33	F	Del	22,5	0,3	N/a	N/a	0.06	no	0
13	34	M	Del	26,8	10,9	7.6	Norm	0.11	no	1
14	31	F	Del	31,0	27,1	44	29	0.2	yes	1
15	48	M	UPD	29	6	31	25.6	0.27	yes	1
16	31	F	Del	24,4	6,7	N/a	N/a	0.21	no	1

^aReflux (pathological > 4.3%)
^bLower Oesophageal Sphincter pressure (normal values: 13–43 mmHg)
^cRelaxation pressure (normal value <15)
^dUnstimulated whole saliva (hyposalivation ≤0.10mL/min)
^eAcidic foods and drinks (sugared and diet soft drinks carbonated/not carbonated) more than once daily

ISSN: 1750-1172