From: Pulmonary hemosiderosis in children with Down syndrome: a national experience
All patients n = 34 | Non-DS group n = 25 | DS group n = 9 | P-value | |
---|---|---|---|---|
n (%) | n (%) | n (%) | ||
Girls | 22 (65%) | 18 (72%) | 4 (44%) | 0.22 |
Boys | 12 (35%) | 7 (28%) | 5 (56%) | 0.22 |
Mean age at the diagnosis | 3.80 ± 3.30 | 4.15 ± 3.27 | 2.92 ± 3.45 | 0.47 |
Family history | ||||
Pulmonary hemosiderosis | 3 (9%) | 3(12%) | 0 (0%) | 0.55 |
Autoimmune disorder | 2 (6%) | 0 (0%) | 2 (22%) | 0.06 |
Personal history | ||||
PAH | 3 (9%) | 0 (0%) | 3 (33%) | 0.01 |
Cardiopathy | 4 (12%) | 0 (0%) | 4 (44%) | 0.003 |
Symptoms at presentation | ||||
Hemoptysis | 16 (47%) | 14 (56%) | 2 (22%) | 0.13 |
Cough | 10 (29%) | 8 (32%) | 2 (22%) | 0.69 |
Dyspnoea | 23 (68%) | 15 (60%) | 9 (100%) | 0.03 |
Pneumonia | 9 (26%) | 6 (24%) | 3 (33%) | 0.67 |
Minimal hemoglobin | ||||
< 7 g/dl | 20 (62.5%) | 14* (61%) | 6 (56%) | 1 |
≥ 7 g/dl | 12 (37.5%) | 9* (39%) | 3 (44%) | 1 |