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Table 1 Main characteristics of the patients with pulmonary hemosiderosis

From: Pulmonary hemosiderosis in children with Down syndrome: a national experience

  All patients n = 34 Non-DS group n = 25 DS group n = 9 P-value
n (%) n (%) n (%)
Girls 22 (65%) 18 (72%) 4 (44%) 0.22
Boys 12 (35%) 7 (28%) 5 (56%) 0.22
Mean age at the diagnosis 3.80 ± 3.30 4.15 ± 3.27 2.92 ± 3.45 0.47
Family history
 Pulmonary hemosiderosis 3 (9%) 3(12%) 0 (0%) 0.55
 Autoimmune disorder 2 (6%) 0 (0%) 2 (22%) 0.06
Personal history
 PAH 3 (9%) 0 (0%) 3 (33%) 0.01
 Cardiopathy 4 (12%) 0 (0%) 4 (44%) 0.003
Symptoms at presentation
 Hemoptysis 16 (47%) 14 (56%) 2 (22%) 0.13
 Cough 10 (29%) 8 (32%) 2 (22%) 0.69
 Dyspnoea 23 (68%) 15 (60%) 9 (100%) 0.03
 Pneumonia 9 (26%) 6 (24%) 3 (33%) 0.67
Minimal hemoglobin
 < 7 g/dl 20 (62.5%) 14* (61%) 6 (56%) 1
 ≥ 7 g/dl 12 (37.5%) 9* (39%) 3 (44%) 1
  1. Abbreviations: DS down syndrome, PAH pulmonary arterial hypertension
  2. *missing data for 2 patients