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Table 3 AHP results - pairwise comparison

From: Revealed preferences towards the appraisal of orphan drugs in Poland - multi criteria decision analysis

MCDA criteria Indication uniqueness Disease rarity Disease severity Adv.tech. Manufacturing technology Therapeutic alternative Sci. evid. Clin.eff Benefits from use of medicine (safety aspects) Cost effectiveness analysis Budget impact analysis Therapy cost HTA recommendations issued elsewhere Rationali-zation analysis
Indication uniqueness 1 0.763157895 0.828571429 7.25 14.5 0.420289855 0.263636364 0.333333333 0.467741935 0.491525424 0.315217391 0.517857143 1.45
Disease rarity 1.310344828 1 1.085714286 9.5 19 0.550724638 0.345454545 0.436781609 0.612903226 0.644067797 0.413043478 0.678571429 1.9
Disease severity 1.206896552 0.921052632 1 8.75 17.5 0.507246377 0.318181818 0.402298851 0.564516129 0.593220339 0.380434783 0.625 1.75
Adv.tech. 0.137931034 0.105263158 0.114285714 1 2 0.057971014 0.036363636 0.045977011 0.064516129 0.06779661 0.043478261 0.071428571 0.2
Manufacturing technology 0.068965517 0.052631579 0.057142857 0.5 1 0.028985507 0.018181818 0.022988506 0.032258065 0.033898305 0.02173913 0.035714286 0.1
Therapeutic alternative 2.379310345 1.815789474 1.971428571 17.25 34.5 1 0.627272727 0.793103448 1.112903226 1.169491525 0.75 1.232142857 3.45
Sci. evid. Clin.eff 3.793103448 2.894736842 3.142857143 27.5 55 1.594202899 1 1.264367816 1.774193548 1.86440678 1.195652174 1.964285714 5.5
Benefits from use of medicine (safety aspects) 3 2.289473684 2.485714286 21.75 43.5 1.260869565 0.790909091 1 1.403225806 1.474576271 0.945652174 1.553571429 4.35
Cost effectiveness analysis 2.137931034 1.631578947 1.771428571 15.5 31 0.898550725 0.563636364 0.712643678 1 1.050847458 0.673913043 1.107142857 3.1
Budget impact analysis 2.034482759 1.552631579 1.685714286 14.75 29.5 0.855072464 0.536363636 0.67816092 0.951612903 1 0.641304348 1.053571429 2.95
Therapy cost 3.172413793 2.421052632 2.628571429 23 46 1.333333333 0.836363636 1.057471264 1.483870968 1.559322034 1 1.642857143 4.6
HTA recommendations issued elsewhere 1.931034483 1.473684211 1.6 14 28 0.811594203 0.509090909 0.643678161 0.903225806 0.949152542 0.608695652 1 2.8
Rationalization analysis 0.689655172 0.526315789 0.571428571 5 10 0.289855072 0.181818182 0.229885057 0.322580645 0.338983051 0.217391304 0.357142857 1
SUM 22.86206897 17.44736842 18.94285714 165.75 331.5 9.608695652 6.027272727 7.620689655 10.69354839 11.23728814 7.206521739 11.83928571 33.15
  1. Sci. evid. clin.eff Scientific evidence for clinical efficiency, Adv.tech. Advancement of technology