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Table 2 Quality of life in 24 CAPS patients at baseline

From: Decreased quality of life and societal impact of cryopyrin-associated periodic syndrome treated with canakinumab: a questionnaire based cohort study

Patient

Age (years)

Gender

Disease duration to start T0 drug (years)

Druga

Treatment duration (months)

EQ-5D

CHQ-physicalb

CHQ-psycho socialb

AIDAI

1001

62.6

M

26.3

Cana 150q6w

51

0.296

  

9.7

1002

39.0

M

UK

Cana 150q6w

51

0.786

   

1003

59.2

F

38.8

Cana 150q8w

16

0.848

  

4.2

1004

59.2

F

0.33

Cana 150 q8w

57

    

1005

34.7

F

 

No

     

1006

28.9

F

UK

Cana 150q8w

1

0.680

   

1007

61.2

F

UK

Cana 150q8w

10

0.813

   

1008

65.0

M

UK

Cana 150q8w

76

0.533

  

0.0

1009

69.1

M

UK

Cana 150q8w

55

0.852

   

2001

24.6

M

20.25

Cana 150q8w

51

0.887

  

0.1

2002

65.8

M

41.5

Cana 150q8w

51

0.695

   

2003

82.0

M

48.4

Ana 100q1d

42

    

2004

52.0

F

39.3

Cana 300q4w

56

0.848

  

2.8

2005

54.6

F

UK

Cana 150q10w

33

0.752

  

0.4

2006

5.6

M

4.7

Cana 100q8w

10

    

2007

15.5

F

11.4

Cana 150q10w

48

1.000

58.7

54.3

 

2008

5.3

F

2.1

Cana 45q8w

29

 

46.9

57.7

0.1

2009

23.0

F

 

No

     

2010

8.2

F

4.1

Cana 90q8w

48

 

49.1

59.3

0.0

2011

8.4

F

3.0

Cana 50q8w

20

 

52.7

61.7

0.0

2012

16.0

M

UK

Ana 100q1d

48

    

2013

16.2

F

4.7

Cana 150q10w

49

0.887

47.9

57.1

 

2014

24.4

F

19.1

Cana 150q8w

57

0.887

  

3.4

2015

23.1

F

19.2

Ana 100q1d

46

    

Median

    

48

    

Mean

     

0.769

51.1

57.1

2.1

  1. Ana anakinra, cana canakinumab, d day, q each, w week
  2. aDrug doses are in mg per time interval, e.g. 150q8w = 150 mg every 8 weeks
  3. bCHQ-PF was only performed in patients < 18 years of age