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Table 4 Associations between ARM and maternal use of thyroid medication

From: Maternal drug use and the risk of anorectal malformations: systematic review and meta-analysis

  Maternal use of thyroid medication  
Ref. First author, year Exposure ORcrude [95% CI] ORadj [95% CI] Adjustment/matching factors
[53] Zwink and Choinitzki, 2015 Thyroid hormone supplementations 1.0 [0.25, 3.74]b
0.4 [0.10, 1.54]c   
[75] Källén and Wikner, 2014 Thyroxin 1.9 [1.00, 1.85]a
[61] Browne, 2009 Anti-thyroid medication 8.6 [1.7, 40.2]
  1. aRisk Ratio (RR)
  2. bCompared to patients with isolated esophageal atresia with or without tracheoesophageal fistula
  3. cCompared to patients with the combined phenotype of esophageal atresia with or without tracheoesophageal fistula and anorectal malformation