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Table 10 Associations between ARM and maternal use of other medical drugs

From: Maternal drug use and the risk of anorectal malformations: systematic review and meta-analysis

 

Maternal use of other medical drugs

 

Ref.

First author, year

Exposure

ORcrude [95% CI]

ORadj [95% CI]

Adjustment/matching factors

[72]

Stoll, 1997

All assessed medicationsc

0.04 [0.004, 0.32]a

–

–

0.03 [0.003, 0.27]b

  

Antispasmodics

Other miscellaneous medication

0.4 [0.16, 1.18]

  

0.5 [0.19, 1.32]

  

[74]

Angerpointer, 1981

All assessed medicationsd

0.7 [0.38, 1.43]

–

–

  1. aCases with no other multiple malformation (isolated)
  2. bCases with other multiple malformations
  3. cIncluded antibiotics, antispasmodics, estrogens and other miscellaneous medication
  4. dIncluded antiemetic, analgetic, laxative and antihypotensive drugs, and iron preparations
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Orphanet Journal of Rare Diseases

ISSN: 1750-1172