Table 2 Baseline characteristics of mothers and offspring in relation to major congenital anomalies
From: Congenital anomalies in neurofibromatosis 1: a retrospective register-based total population study
Characteristic | No major congenital anomaly (n = 4886) | Major congenital anomaly (n = 107) | P |
|---|---|---|---|
Age (y) | 29.1 ± 5.2 | 29.1 ± 5.7 | .946 |
Smoking during pregnancy | .127 | ||
Yes | 722 (14.8) | 22 (20.6) | |
No | 4047 (82.8) | 84 (78.5) | |
Missing | 117 (2.4) | 1 (0.9) | |
Married or cohabiting | .255 | ||
Yes | 4439 (90.9) | 94 (87.9) | |
No | 415 (8.5) | 12 (11.2) | |
Missing | 32 (0.7) | 1 (0.9) | |
Socioeconomic positiona | |||
Upper white | 596 (15.1) | 16 (16.7) | .771 |
Lower white | 1717 (43.5) | 37 (38.5) | .225 |
Blue-collar | 764 (19.3) | 26 (27.1) | .098 |
Other | 630 (15.9) | 14 (14.6) | .634 |
Missing | 244 (6.2) | 3 (3.1) | |
Parity | .171 | ||
1+ | 2965 (60.7) | 55 (51.4) | |
0 | 1896 (38.8) | 52 (48.6) | |
Missing | 25 (0.5) | 0 (0.0) | |
Sex, offspring | .993 | ||
Male | 2659 (54.4) | 58 (54.2) | |
Female | 2227 (45.6) | 49 (45.8) | |
Gestational age, offspring (weeks) | 39.8 ± 1.7 | 39.4 ± 2.1 | .072 |
Missing | 33 (0.7) | 0 (0.0) | |
Birth size | |||
SGA | 245 (5.0) | 14 (13.1) | <.001 |
AGA | 4320 (88.4) | 85 (79.4) | .002 |
LGA | 277 (5.7) | 8 (7.5) | .521 |
Missing | 44 (0.9) | 0 (0.0) |