From: Congenital anomalies in neurofibromatosis 1: a retrospective register-based total population study
Characteristic | Mothers of offspring with NF1 (n = 443) | Mothers of control children (n = 4550) | P |
---|---|---|---|
Age (y) | 29.5 ± 5.4 | 29.0 ± 5.1 | .071 |
Smoking during pregnancy | .300 | ||
Yes | 73 (16.5) | 671 (14.7) | |
No | 360 (81.3) | 3771 (82.9) | |
Missing | 10 (2.3) | 108 (2.4) | |
Married or cohabiting | .123 | ||
Yes | 392 (88.5) | 4141 (91.0) | |
No | 46 (10.4) | 381 (8.4) | |
Missing | 5 (1.1) | 28 (0.6) | |
Socioeconomic positiona | |||
Upper white | 40 (11.2) | 572 (15.5) | .048 |
Lower white | 151 (42.2) | 1603 (43.5) | .857 |
Blue-collar | 84 (23.5) | 706 (19.1) | .035 |
Other | 55 (15.4) | 589 (16.0) | .874 |
Missing | 28 (7.8) | 219 (5.9) | |
Parity | .669 | ||
1+ | 278 (62.8) | 2742 (60.3) | |
0 | 162 (36.6) | 1786 (39.3) | |
Missing | 3 (0.7) | 22 (0.5) | |
Sex, offspring | .784 | ||
Male | 241 (54.4) | 2476 (54.4) | |
Female | 202 (45.6) | 2074 (45.6) | |
Gestational age, offspring (weeks) | 39.2 ± 1.9 | 39.8 ± 1.6 | <.001 |
Missing | 4 (0.9) | 29 (0.6) | |
Birth size, offspring | |||
SGA | 29 (6.5) | 230 (5.1) | .241 |
AGA | 363 (81.9) | 4042 (88.8) | <.001 |
LGA | 46 (10.4) | 239 (5.3) | <.001 |
Missing | 5 (1.1) | 39 (0.9) |