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Table 1 Baseline characteristics of mothers and offspring

From: Congenital anomalies in neurofibromatosis 1: a retrospective register-based total population study

Characteristic

Mothers of offspring with NF1 (n = 443)

Mothers of control children (n = 4550)

P

Age (y)

29.5 ± 5.4

29.0 ± 5.1

.071

Smoking during pregnancy

  

.300

 Yes

73 (16.5)

671 (14.7)

 

 No

360 (81.3)

3771 (82.9)

 

 Missing

10 (2.3)

108 (2.4)

 

Married or cohabiting

  

.123

 Yes

392 (88.5)

4141 (91.0)

 

 No

46 (10.4)

381 (8.4)

 

 Missing

5 (1.1)

28 (0.6)

 

Socioeconomic positiona

   

 Upper white

40 (11.2)

572 (15.5)

.048

 Lower white

151 (42.2)

1603 (43.5)

.857

 Blue-collar

84 (23.5)

706 (19.1)

.035

 Other

55 (15.4)

589 (16.0)

.874

 Missing

28 (7.8)

219 (5.9)

 

Parity

  

.669

 1+

278 (62.8)

2742 (60.3)

 

 0

162 (36.6)

1786 (39.3)

 

 Missing

3 (0.7)

22 (0.5)

 

Sex, offspring

  

.784

 Male

241 (54.4)

2476 (54.4)

 

 Female

202 (45.6)

2074 (45.6)

 

Gestational age, offspring (weeks)

39.2 ± 1.9

39.8 ± 1.6

<.001

 Missing

4 (0.9)

29 (0.6)

 

Birth size, offspring

   

 SGA

29 (6.5)

230 (5.1)

.241

 AGA

363 (81.9)

4042 (88.8)

<.001

 LGA

46 (10.4)

239 (5.3)

<.001

 Missing

5 (1.1)

39 (0.9)

 
  1. Data are n (%) or mean ± standard deviation. SGA small for gestational age, AGA appropriate for gestational age, LGA large for gestational age
  2. a data available since 1991 (n = 358 for mothers of offspring with NF1 and 3689 for mothers of control children)