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Table 2 Muscle fiber type distribution and cross-sectional areas of muscle fibers at baseline, pre-training and post-training in Huntington disease (HD) patients and healthy controls

From: Effects of endurance training on skeletal muscle mitochondrial function in Huntington disease patients

 

HD patients (n = 13)

Controls (n = 11)

 

Baseline

Pre-Training

Post-Training

Pre-Training

Post-Training

Muscle fiber type distribution

 MyHC-1 (%)

59.0 ± 13.9

57.0 ± 13.8

60.2 ± 10.0

56.7 ± 9.7

53.5 ± 12.2

 MyHC-2A (%)

33.3 ± 9.5

30.9 ± 10.6

32.5 ± 10.7

31.7 ± 7.5

34.9 ± 12.9

 MyHC-2X (%)

7.8 ± 6.7

12.1 ± 10.0

7.3 ± 5.8

11.6 ± 10.0

11.6 ± 7.3

  1. Values are mean ± SD. MyHC, myosin heavy chain