Fig. 2From: Integrating molecular and structural findings: Wnt as a possible actor in shaping cognitive impairment in Cornelia de Lange syndromeExample of brain abnormalities in a fetus at 25Â weeks of gestation. Note the size reduction of the cerebellum with severe volume loss; the immaturity of sulcal pattern with slight underdevelopment of the frontal operculae for the gestational age, resulting in uncovering of the insula; the abnormalities of the corpus callosum that appears thin (in the trunk area) and short (with absence of the genu)Back to article page