Skip to main content

Table 2 Summary of prevalence studies

From: Unmet clinical needs and burden in Angelman syndrome: a review of the literature

  Target No. Positive/No. Tested Prevalence Rates Found Methodology Country
Clayton-Smith, 1995 [20] Not reported Not reported 1:62,000 Medical record review from 1989 to 1992 (only those under age 29) United Kingdom
Kyllerman, 1995 [115] Individuals with epilepsy and intellectual disability 4/48,873 1:12,000 Genetic testing of all children with epilepsy ages 6–13 with intellectual disability Sweden
Mertz et al., 2013 [18] All identified patients compared with livebirth records 51/1,253,599 1:24,580 Review of records in the Danish National Patient Registry and the Danish Cytogenetic Central Registry from 1991 to 2009 Denmark
Oiglane-Shlik et al., 2006 [21] All identified patients compared with livebirth records 7/3,650,266 1:52,181 Country-wide search for children with known Angelman syndrome or Prader-Willi syndrome born between 1984 and 2004 Estonia
Petersen et al., 1995 [17] Individuals seen in a neuropediatric clinic 5/500,000 1:10,000 Individuals in neuropediatric clinic from 1983 to 1991 Denmark
Thomson, et al., 2006 [19] All identified patients compared with livebirth records 26/1,050,000 1:40,000 Retrospective, quantitative review of Disability Services Commission files from 1953 to 2003 Australia