Table 2 Summary of prevalence studies
From: Unmet clinical needs and burden in Angelman syndrome: a review of the literature
| Â | Target | No. Positive/No. Tested | Prevalence Rates Found | Methodology | Country |
|---|---|---|---|---|---|
Clayton-Smith, 1995 [20] | Not reported | Not reported | 1:62,000 | Medical record review from 1989 to 1992 (only those under age 29) | United Kingdom |
Kyllerman, 1995 [115] | Individuals with epilepsy and intellectual disability | 4/48,873 | 1:12,000 | Genetic testing of all children with epilepsy ages 6–13 with intellectual disability | Sweden |
Mertz et al., 2013 [18] | All identified patients compared with livebirth records | 51/1,253,599 | 1:24,580 | Review of records in the Danish National Patient Registry and the Danish Cytogenetic Central Registry from 1991 to 2009 | Denmark |
Oiglane-Shlik et al., 2006 [21] | All identified patients compared with livebirth records | 7/3,650,266 | 1:52,181 | Country-wide search for children with known Angelman syndrome or Prader-Willi syndrome born between 1984 and 2004 | Estonia |
Petersen et al., 1995 [17] | Individuals seen in a neuropediatric clinic | 5/500,000 | 1:10,000 | Individuals in neuropediatric clinic from 1983 to 1991 | Denmark |
Thomson, et al., 2006 [19] | All identified patients compared with livebirth records | 26/1,050,000 | 1:40,000 | Retrospective, quantitative review of Disability Services Commission files from 1953 to 2003 | Australia |