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Fig. 2 | Orphanet Journal of Rare Diseases

Fig. 2

From: KH176 under development for rare mitochondrial disease: a first in man randomized controlled clinical trial in healthy male volunteers

Fig. 2

Mean plasma concentrations of KH176 and its metabolite KH176m after single and multiple dose administration to healthy subjects. a. Plasma-concentration/time curve of KH176 for the SAD study (fasted state). b. Plasma-concentration/time curve of KH176m for the SAD study (fasted state). c. Plasma-concentration/time curve of KH176 for the MAD study. d. Plasma-concentration/time curve of KH176m for the MAD study. Loglinear scale

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