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Table 3 Correlation between MMSE, FAB and clinical data

From: Cognitive impairment profile in adult patients with Niemann pick type C disease

 

MMSE

FAB

Age of onset

R2 = −0.04 (p = 0.87)

R2 = −0.3 (p = 0.23)

Age at first examination

R 2 = −0.57 ( p  = 0.01)

R2 = 0.27 (p = 0.28)

Disease duration

R 2 = −0.49 ( p = 0.03)

R2 = −0.07 (p = 0.77)

Education level

R2 = 0.10 (p = 0.69)

R2 = 0.14 (p = 0.59)

Presence of psychosis

R2 = 0.27 (p = 0.28)

R2 = 0.20 (p = 0.41)

Walking score

R2 = 0.2 (p = 0.45)

R2 = 0.19 (p = 0.48)

Manipulation score

R 2  = 0.51 ( p = 0.04)

R2 = 0.12 (p = 0.66)

Dysarthria score

R 2 = 0.49 ( p = 0.05)

R 2 = 0.59 ( p = 0.02)

Deglutition score

R2 = 0.2 (p = 0.45)

R2 = 0.13 (p = 0.65)

Duration of miglustat

R2 = −0.46 (p = 0.1)

R2 = −0.17 (p = 0.57)

Time between the onset of disease and the initiation of miglustat

R2 = −0.28 (p = 0.25)

R2 = 0.1 (p = 0.71)

  1. A probability value of <0.05 was considered significant
  2. Significant results are written in bold
  3. FAB frontal assessment battery, MMSE mini-mental state examination