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Fig. 3 | Orphanet Journal of Rare Diseases

Fig. 3

From: Prevalence of TECTA mutation in patients with mid-frequency sensorineural hearing loss

Fig. 3

Modeling of possibly pathogenic variants in TECTA. a ZP-N dimer structure of TECTA. White and light green colors represent monomers. Light blue lines, hydrogen bonds; yellow, the side chain of Y1900; purple, K1807; arrowheads, hydrogen bonds between Y1900 and K1807; arrows, hydrogen bonds connecting ZP-N domains. b Monomer structure of wild type ZP-N. c Monomer structure of ZP-N with p.Y1900C mutation. The side chain of C1900 is indicated in orange

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