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Table 1 Patient demographics and medical history, based on patients’ recollections of events

From: The impact of lipoprotein lipase deficiency on health-related quality of life: a detailed, structured, qualitative study

 

Patient 1

Patient 2

Patient 3

Sex

Female

Male

Female

Age (years)

64

28

42

Age at LPLD symptom onset (years)

13

Primary school age

Early 30s

Age at diagnosis of LPLD (years)

Early 50s (diagnosis of hyperlipidaemia type I/V and acute/chronic pancreatitis at 18 years old)

Young age

Early 40s

Number of acute attacks of pancreatitis requiring hospitalisation

>15a

102b (requiring hospitalisation over 5 years)

5 (2 admissions to ITU; 2 to HDU; 1 admission to a ward)

Medicationsc taken at home for LPLD symptoms

Antox®, black garlic

Tramadol, cyclizine, Deep Heat® patches

Statins, fenofibrate, omega-3 capsules

In-hospital medications/management during attacks of pancreatitis

IV fluids and morphine, slow re-introduction of food

IV fluids, morphine and cyclizine followed by IV paracetamol, nil by mouth for 1–2 days

Analgesic medications, total parenteral nutrition

Comorbidities

PVD, hypertension, IBS

None

Type 2 diabetes

Family members with LPLD

Sister had a child (son) who died from high levels of lipids in the liver (formal diagnosis unknown)

Yes (sister)

Yes (sister)

  1. HDU high-dependency unit, IBS irritable bowel syndrome, ITU intensive therapy unit, IV intravenous, LPLD lipoprotein lipase deficiency, PVD peripheral vascular disease
  2. aThis number may be underestimated given that patient 1 experienced one attack per month in her late teens and early 20s
  3. bThis number was estimated by the patient
  4. cPharmacological and alternative