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Table 3 Cut-off values for HOMA-IR, BMI (kg/m2), and BMI (SDS) as predictive values of T2DM development in PWS

From: Prevalence and risk factors for type 2 diabetes mellitus with Prader–Willi syndrome: a single center experience

 

Cut off point

Area under the curve (95% CI)

Sensitivity (95% CI)

Specificity (95% CI)

HOMA-IR

2.7*

0.843

90.48

76.19

BMI (kg/m2)

28.49*

0.765

78.57

71.43

BMI (SDS)

1.73*

0.757

83.33

61.90

  1. Abbreviations: T2DM type 2 Diabetes Mellitus, PWS Prader-Willi syndrome, HOMA-IR homeostasis model assessment, BMI body mass index, CI confidence interval, SDS standard deviation score
  2. *Significant association was classified as p < 0.0001
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Orphanet Journal of Rare Diseases

ISSN: 1750-1172