Fig. 3From: Nuclear envelopathies: a complex LINC between nuclear envelope and pathologyPredicted structure of ZMPSTE24 protease. ZMPSTE24 is a transmembrane protein located in the Outer Nuclear Membrane composed of seven hydrophobic domains (1 to 7, a catalytic domain (HELGH residues), and an endoplasmic reticulum retention motif (TMKQH residues)Back to article page