Is age a risk factor for liver disease and metabolic alterations in ataxia Telangiectasia patients?

Table 3 Comparison of the variables in A-T group and control group

Variable		A-T Group (n = 18)	Controls (n = 17)	p Value
Total cholesterol	mg/dL	177.4 ± 33.3	170.0 ± 25.4	0.448^a
LDL-c	mg/dL	115.4 ± 32.3	107.6 ± 22.3	0.412^a
HDL-c	mg/dL	43.5 ± 10.8	45.2 ± 8.1	0.596^a
Triglycerides	mg/dL	94.1 ± 47.2	91.7 ± 45.8	0.880^a
Non-HDL-cholesterol	mg/dL	134.2 ± 35.7	124.8 ± 25.6	0.377^a
Total cholesterol/HDL-c	mg/dL	4.3 ± 1.4	3.9 ± 0.9	0.265^a
LDL/HDL	mg/dL	2.8 ± 1.1	2.5 ± 0.8	0.272^a
Apo A-I	mg/mL	130.8 ± 27.2	138.8 ± 19.8	0.330^a
Apo B	mg/mL	274.1 ± 184.4	167.0 ± 46.0	0.027 ^a
Apo B/Apo AI	mg/mL	2.1 ± 1.4	1.2 ± 0.3	0.018 ^a
LDL/ApoB	mg/mL	0.56 ± 0.42	0.67 ± 0.15	0.327^a
Lp(a)	pg/mL	182.8 (31.2;585.8)	31.2 (31.2;334.9)	0.001 ^b
LDLox	pg/mL	2610.0 ± 985.0	2338.4 ± 982.6	0.533^a
sdLDL-c	mmol/L	3.3 ± 0.9	3.2 ± 0.9	0.641^a

^aSignificance level of the t-Student test.^b Significance level of the Mann-Whitney test
Legend: LDL-c low density lipoprotein cholesterol, HDL-c high density lipoprotein cholesterol, TC total cholesterol, Apo AI apolipoprotein A, Apo B apolipoprotein B, LDLox oxidized LDL and Lp(a) [lipoprotein (a)]
The bold text means the p-value of satistical tests (t-Student¹ or Mann-Witney² are less than p< 0,05 (there was statistical significance)

ISSN: 1750-1172