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Table 3 Surface accessibility of native and mutant IDUA variants that are selected for structural analysis

From: Phenotype prediction for mucopolysaccharidosis type I by in silico analysis

SNP ID AA AA position RSA ASA Z-fit score for RSA prediction Class assignment
rs121965021 P 533 0.341 48.43 −1.149 Buried
  R   0.344 78.73 −0.651 Buried
rs371397270 D 349 0.241 34.699 −0.488 Buried
  G   0.392 30.819 −1.405 Exposed
rs775816150 T 374 0.095 13.149 −1.852 Buried
  P   0.233 33.134 −1.134 Buried
rs772416503 P 496 0.105 14.928 0.247 Buried
  R   0.164 37.533 −0.253 Buried
rs121965033 L 346 0.031 5.603 0.342 Buried
  R   0.108 24.09 −0.954 Buried
  1. AA amino acid, RSA relative surface accessibility, ASA absolute surface accessibility