Fig. 6
From: Neural stem cells for disease modeling of Wolman disease and evaluation of therapeutics
DT and HPBCD combination treatment have an additive effect on reducing lysosomal staining in WD NSCs. a LysoTracker (green) and nuclear (blue) staining images with quantitation of DT/HPBCD combination treatment. b Amplex red assay for cholesteryl ester content of WD NSCs treated with DT and HPBCD combination. Data are displayed as mean ± SD. Statistical significance was calculated as each combination treatment compared against vehicle treatment in the same WD cell line