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Fig. 6 | Orphanet Journal of Rare Diseases

Fig. 6

From: Neural stem cells for disease modeling of Wolman disease and evaluation of therapeutics

Fig. 6

DT and HPBCD combination treatment have an additive effect on reducing lysosomal staining in WD NSCs. a LysoTracker (green) and nuclear (blue) staining images with quantitation of DT/HPBCD combination treatment. b Amplex red assay for cholesteryl ester content of WD NSCs treated with DT and HPBCD combination. Data are displayed as mean ± SD. Statistical significance was calculated as each combination treatment compared against vehicle treatment in the same WD cell line

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