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Fig. 5 | Orphanet Journal of Rare Diseases

Fig. 5

From: Neural stem cells for disease modeling of Wolman disease and evaluation of therapeutics

Fig. 5

DT and HPBCD treatment reduces lysosomal staining in WD NSCs. a LysoTracker (green) and nuclear (blue) staining images with quantitation of DT-treated NSCs. b LysoTracker (green) and nuclear (blue) staining images with quantitation of HPBCD-treated NSCs. c Amplex red assay for cholesteryl ester content of WD NSCs treated with DT. d Amplex red assay for cholesteryl ester content of WD NSCs treated with HPBCD. Data are displayed as mean ± SD. Statistical significance was calculated as each concentration of compound compared against vehicle in the same WD cell line

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