Fig. 4
From: ATM splicing variants as biomarkers for low dose dexamethasone treatment of A-T
ATMdexa1 transcript family. Amplicons obtained by 5′ nuclease qPCR of the compassionate EryDex samples analysed by electrophoretic gel. Lane M, DNA ladder. Lanes 1–16 contain the qPCR products from five patient samples collected at different time points. The white arrows show the ATMdexa1 PCR product, while the amplicon in all lanes at 115 bp is the HPRT1 PCR product. The other PCR products, with the exception of non-specific amplicons, represent ATMdexa1 splicing variants: green arrow splicing SDR 4–51; yellow arrows splicing 4–53; red arrows splicing 3–52; cyan arrow splicing SDR 3–52 and magenta arrow splicing 2–52