Fig. 1
From: ATM splicing variants as biomarkers for low dose dexamethasone treatment of A-T
ATMdexa1 expression levels in patients treated with EryDex. Two qPCR assays were set up for ATMdexa1 estimation in whole blood. AT, untreated patients with AT n = 6; AT Dexa, patients with AT and treated with EryDex n = 10; WT, healthy volunteers n = 6. The first qPCR assay is based on SYBR green chemistry PCR (panel a) while a second one is built on 5′ exonuclease qPCR (panel b). In both settings, ATMdexa1 expression levels were detectable only in AT patients treated with EryDex. The transcript was undetectable in untreated AT patients and in healthy volunteers