From: Pain and quality of life evaluation in patients with localized epidermolysis bullosa simplex
Variables | Number | Side effects | efficacy yes, n | Treatment compliance, n | ||
---|---|---|---|---|---|---|
Total | Children | Adults | ||||
Oral treatment | ||||||
Grade 1 analgesic | ||||||
Paracetamol | 36 | 20 | 16 | 1 | 18 | 2 |
NSAIDs | 12 | 2 | 10 | 2 | 12 | 0 |
Grade 2 analgesic | ||||||
Moderate Opioids | 3 | 0 | 3 | 2 | 2 | 0 |
Tramadol | 5 | 4 | 1 | 1 | 5 | 3 |
Codein Paracetamol | 5 | 1 | 4 | 2 | 4 | 1 |
Analgesic for neuropathic pain | ||||||
Tricyclic antidepressant (Amitriptyline) | 1 | 1 | 0 | 0 | 1 | 1 |
Anxiolytic | ||||||
Hydroxyzine (Atarax®) | 1 | 1 | 0 | 1 | 0 | 0 |
Local treatment | ||||||
lidocaine 2.5% and prilocaine 2.5% (EMLA®) | 5 | 4 | 1 | 0 | 2 | 2 |
5% lidocaine plasters (VERSATIS®) | 6 | 3 | 3 | 0 | 6 | 4 |
No treatment | ||||||
Oral | 19 | 6 | 13 | |||
Local | 46 | 19 | 27 |