Table 3 Events related to treatment with gemfibrozil
| Â | Causal relationship | Causal relationship |
|---|---|---|
Probable | Not established | |
General: | weight loss | Â |
Cardiac | extrasystoles | Â |
Gastrointestinal | cholestatic jaundice | pancreatitis |
| Â | hepatoma | |
| Â | colitis | |
Central Nervous System | dizziness | confusion |
Somnolence | convulsions | |
Paresthesia | syncope | |
peripheral neuritis | Â | |
decreased libido | Â | |
depression | Â | |
headache | Â | |
Eye | blurred vision | retina edema |
Genitourinary | impotence | decreased male fertility |
| Â | renal dysfunction | |
Musculoskeletal | myopathy | Â |
myasthenia | Â | |
myalgia | Â | |
painful extremities | Â | |
arthralgia | Â | |
synovitis | Â | |
rhabdomyolysis | Â | |
Clinical Laboratories | increased creatine | positive antinuclear antibody |
Phosphokinase | Â | |
increased bilirubin | Â | |
increased liver | Â | |
transaminases (AST, ALT) | Â | |
increased alkaline | Â | |
phosphatase | Â | |
Hematopoietic | anemia | thrombocytopenia |
leukopenia | Â | |
bone marrow hypoplasia | Â | |
eosinophilia | Â | |
Immunologic | angioedema | anaphylaxis |
laryngeal edema | Lupus-like syndrome | |
urticarial | vasculitis | |
Integumentary | exfoliative dermatitis | alopecia |
Rash | photosensitivity | |
dermatitis | Â | |
pruritus | Â |