| |
Causal relationship
|
Causal relationship
|
|---|
|
Probable
|
Not established
|
|---|
|
General:
|
weight loss
| |
|
Cardiac
|
extrasystoles
| |
|
Gastrointestinal
|
cholestatic jaundice
|
pancreatitis
|
| |
hepatoma
|
| |
colitis
|
|
Central Nervous System
|
dizziness
|
confusion
|
|
Somnolence
|
convulsions
|
|
Paresthesia
|
syncope
|
|
peripheral neuritis
| |
|
decreased libido
| |
|
depression
| |
|
headache
| |
|
Eye
|
blurred vision
|
retina edema
|
|
Genitourinary
|
impotence
|
decreased male fertility
|
| |
renal dysfunction
|
|
Musculoskeletal
|
myopathy
| |
|
myasthenia
| |
|
myalgia
| |
|
painful extremities
| |
|
arthralgia
| |
|
synovitis
| |
|
rhabdomyolysis
| |
|
Clinical Laboratories
|
increased creatine
|
positive antinuclear antibody
|
|
Phosphokinase
| |
|
increased bilirubin
| |
|
increased liver
| |
|
transaminases (AST, ALT)
| |
|
increased alkaline
| |
|
phosphatase
| |
|
Hematopoietic
|
anemia
|
thrombocytopenia
|
|
leukopenia
| |
|
bone marrow hypoplasia
| |
|
eosinophilia
| |
|
Immunologic
|
angioedema
|
anaphylaxis
|
|
laryngeal edema
|
Lupus-like syndrome
|
|
urticarial
|
vasculitis
|
|
Integumentary
|
exfoliative dermatitis
|
alopecia
|
|
Rash
|
photosensitivity
|
|
dermatitis
| |
|
pruritus
| |
- SPC (Standard of Product Characteristics) of LOPID® (Gemfibrozil Tablets, USP) by Pfizer, Revised March 2016
