Table 2 Safety of gemfibrozil in children
Age | Dose (duration) | Purpose | Effect | Side effects (reference) |
|---|---|---|---|---|
Children with metabolic Syndrome, n = 47 | 600 mg 2 x /day (8 months) | reduce lipids | ↓triglycerides ↑HDL | 1AE muscle pain n = 2 (52) |
Late preterm & term neonates with jaundice n = 97 (49 active, 48 placebo) | 60 mg/kg 2 doses (1 day) | reduce light therapy time, decrease bilirubin | no effect | none (51) |
Infants with Chylomicronemia* Syndrome, n = 2 | 300 mg 2 x /day (3, 7 years) | improve jaundice | ↓pancreatitis | none (54) |
Children with hyperlipidemia & nephrotic syndrome, n=12 (7 active, 5 placebo) | 150 mg 2 x/day (4 months) | reduce lipids | ↓cholesterol ↓triglycerides | none (50) |
Age 13 female n = 1 | 3 weeks | reduce lipids | NA | LABD (55) |