The cost of severe haemophilia in Europe: the CHESS study

Table 1 National costs for CHESS resource units

Resource item	Baseline unit price (EUR)
Resource item	France^c	Germany^d	Italy^e	Spain^f	UK^g
Direct costs
Ambulatory care
Haematologist visit (per visit)	25.99–45.99	20.88	27.32–23.17	65.69–113.54	124.71–228.57
Nurse visit (per visit)	81.74	34.28–38.42	15.11	20.92–37.46	19.36
Other specialist visit (per visit)	14.99–45.99	7.30–228.88	18.21–27.32	16.42–160	65.91–612.03
Blood test (per test)	1.89–53.96	0.50–112.50	2.11–17.22	4.78–98.37	4.29–7.67
Other test/examination (per test)	10.79–69.00	5.50–124.60	2.19–134.27	7.49–249.21	1.69–228.24
Drug (per IU)^a	0.72	0.85–2.08	0.62–1.23	0.39–0.90	0.44–0.84
Hospitalisation
Target joint (per procedure)	28.81–534.40	12.02–1,719.43	33.48–1,032.91	169.75–2,156.33	1,161.93–8,397.52
Bleed event: ward stay (per day)	290.85	514.29	265	708.71	562.88
Bleed event: ICU stay (per day)	1,174.60	1,265	366	1,559.24	1,056.82
Professional caregiver (per hour)	8.30	27.43	7.39	13.66	24.56
Indirect costs^b
Wage (patient/caregiver) (per hour)	24.64	27.15	17	16.35	27.75
Petrol (per mile)	0.53	0.54	0.63	0.50	0.63
Scheduled ambulance (per mile)	1.36	-	-	-	-

Note. Ranges presented where more than one price is possible; ICU: intensive care unit; IU: International Units
^aDrug costs sourced via Study Steering Committee liaison and correspondence with domestic drug providers
^bCosts for OTC medications, medical devices/aids, alternative therapies, and transfer payment entitlements provided directly by the respondent
^cSources: Ameli, sante.gouv, ViDAL.fr, Catalogue Commun des actes médicaux
^dSources: Kbv.de, meinpharmaversand.de, Einheitlicher Bewertungsmaßstab, rote-liste service
^eSources: AIFA, agenziafarmaco.gov
^fSources: Oblikue e-salud, Agencia espanola de medicamentos y productos sanitarios
^gSources: National Schedule of Reference Costs, Electronic Medicines Compendium

ISSN: 1750-1172