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Table 3 Gait characteristics per walking condition

From: Quantification of gait in mitochondrial m.3243A > G patients: a validation study

Condition

Variable

Patients

(N = 36)

Controls

(N = 50)

Difference between Patients and Controls

(p-value)

Normal walking

Velocity (m/s)

1 · 11 ± 0 · 19

1 · 32 ± 0 · 16

<0 · 001

Step length (m)

0 · 59 ± 0 · 08

0 · 69 ± 0 · 06

<0 · 001

Step time (s)

0 · 54 ± 0 · 05

0 · 53 ± 0 · 05

0 · 135

Step width (m)

0 · 10 ± 0 · 03

0 · 09 ± 0 · 03

0 · 406

Step length variability (mm)

29 · 1 ± 14 · 4

25 · 2 ± 7 · 8

0 · 241

Step time variability (ms)

28 · 6 ± 33 · 2

19 · 2 ± 7 · 1

0 · 013

Step width variability (mm)

25 · 4 ± 7 · 4

20 · 1 ± 5 · 7

<0 · 001

Step Length Asymmetry (mm)

16 · 3 ± 14 · 3

15 · 4 ± 11 · 4

0 · 986

Step Time Asymmetry (ms)

8 · 6 ± 8 · 7

8 · 0 ± 8 · 3

0 · 759

Dual task

Velocity (m/s)

0 · 93 ± 0 · 21

1 · 16 ± 0 · 23

<0 · 001

Step length (m)

0 · 57 ± 0 · 08

0 · 65 ± 0 · 07

<0 · 001

Step time (s)

0 · 64 ± 0 · 16

0 · 58 ± 0 · 12

0 · 036

Step width (m)

0 · 10 ± 0 · 04

0 · 10 ± 0 · 03

0 · 703

Step length variability (mm)

40 · 6 ± 24 · 4

29 · 3 ± 9 · 6

0 · 002

Step time variability (ms)

79 · 4 ± 106 · 2

37 · 8 ± 59 · 6

<0 · 001

Step width variability (mm)

27 · 2 ± 9 · 0

23.0 ± 6 · 7

0 · 019

Step Length Asymmetry (mm)

19 · 2 ± 21 · 9

16.7 ± 14 · 4

0 · 875

Step Time Asymmetry (ms)

18 · 6 ± 21 · 8

15.4 ± 18 · 2

0 · 578

Post exercise

Velocity (m/s)

1 · 21 ± 0 · 18

1 · 45 ± 0 · 15

<0 · 001

Step length (m)

0 · 62 ± 0 · 08

0 · 72 ± 0 · 06

<0 · 001

Step time (s)

0 · 52 ± 0 · 05

0 · 50 ± 0 · 04

0 · 070

Step width (m)

0 · 10 ± 0 · 03

0 · 09 ± 0 · 02

0 · 391

Step length variability (mm)

27 · 7 ± 10 · 2

24 · 4 ± 7 · 8

0 · 109

Step time variability (ms)

20 · 4 ± 10 · 7

16 · 8 ± 5 · 3

0 · 168

Step width variability (mm)

23 · 6 ± 7 · 2

21 · 0 ± 5 · 6

0 · 089

Step Length Asymmetry (mm)

17 · 8 ± 14 · 0

15 · 9 ± 11 · 3

0 · 796

Step Time Asymmetry (ms)

10 · 3 ± 11 · 8

8 · 2 ± 7 · 2

0 · 666

After rest

Velocity (m/s)

1 · 18 ± 0 · 18

1 · 42 ± 0 · 16

<0 · 001

Step length (m)

0 · 60 ± 0 · 08

0 · 71 ± 0 · 06

<0 · 001

Step time (s)

0 · 52 ± 0 · 05

0 · 50 ± 0 · 04

0 · 102

Step width (m)

0 · 10 ± 0 · 03

0 · 09 ± 0 · 02

0 · 439

Step length variability (mm)

26 · 4 ± 12 · 1

20 · 7 ± 7 · 6

0 · 023

Step time variability (ms)

19 · 1 ± 9 · 6

15 · 2 ± 4 · 4

0 · 054

Step width variability (mm)

24 · 0 ± 9 · 1

19 · 5 ± 5 · 6

0 · 027

Step Length Asymmetry (mm)

15 · 8 ± 14 · 6

16 · 4 ± 10 · 1

0 · 365

Step Time Asymmetry (ms)

11 · 2 ± 12 · 0

8 · 0 ± 7 · 3

0 · 409

  1. Differences in gait characteristics between patients with the m.3243A > G mutation and healthy controls, significant p-values below p = 0 · 05 are shown in italic, p-values below p = 0 · 001 are shown in bold