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Table 4 Comparison of the groups on the basis of renal functions and acute phase parameters

From: Tocilizumab in the treatment of twelve cases with aa amyloidosis secondary to familial mediterranean fever

 

All group(n = 12)

AA + FMF(n = 8)

AA + FMF + co-existing diseases(n = 4)

Before treatment

After treatment

Before treatment

After treatment

Before treatment

After treatment

Creatinine (mg/dl) (Female: 0.5–0.9; Male:0.7–1.2)

1.1 ± 0.9

1.0 ± 0.6

1.2 ± 1.1

1.0 ± 0.7

0.9 ± 0.4

1.0 ± 0.4

GFR (ml/min) (71–151)

111.7 ± 50.1

108.9 ± 54.8

118.1 ± 59.4

122.1 ± 62.8

99.0 ± 25.5

82.7 ± 20.4

Proteinuria (mg/day)

6537.6 ± 6526.0

4745.5 ± 5462.7

7920.1 ± 7576.9

5417.9 ± 6585.0

3772.6 ± 2628.7

3400.6 ± 2149.8

CRP (0–5 mg/L)

18.1 ± 19.5

5.8 ± 7.1

20.5 ± 23.3

4.1 ± 5.2

13.3 ± 9.0

9.3 ± 10.0

Sedimentation (0–20 mm/h)

48.7 ± 31.0

27.8 ± 28.3

54.9 ± 34.2

24.0 ± 22.4

36.3 ± 22.0

35.5 ± 40.5