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Table 3 Investigations performed at time of diagnosis

From: Childhood interstitial lung diseases in immunocompetent children in Australia and New Zealand: a decade’s experience

  N (%) All cases Diagnosis < 2 years Diagnosis ≥ 2 years
   No.reported
(Max 107)
N (%) No. reported (Max 66)a N (%) No. reported (Max 40)a
Investigations performed
Chest X-Ray 99 (100.0) 99 63 (100.0) 63 35 (100.0) 35
  Interstitial infiltrates 41 (55.4) 74 27 (54.0) 50 14 (58.3) 24
  Alveolar infiltrates 22 (35.5) 62 13 (29.5) 44 9 (50.0) 18
CT Scan 95 (95.0) 100 55 (93.2) 59 39 (97.5) 40
   with controlled ventilation 40 (51.3) 78 30 (69.8) 43 10 (28.6) 35
  expiratory views 57 (79.1) 72 32 (76.2) 42 25 (83.3) 30
CT scan findings
  Reticular nodular infiltrates 16 (30.7) 52 6 (18.7) 32 10 (50.0) 20
  Ground glass pattern 52 (71.2) 73 32 (71.1) 45 20 (71.4) 28
  Honey comb pattern 6 (13.1) 46 1 (3.4) 29 5 (29.4) 17
Lung Biopsy 79 (75.2) 105 52 (81.3) 64 26 (65.0) 40
   Biopsy Method
   Open lung biopsy 23 (36.5) 63 18 (43.9) 41 5 (22.7) 22
   Video assisted thoracoscopic 40 (63.5) 63 23 (56.1) 41 17 (77.3) 22
   Transbronchial 0 63 0 41 0 22
Echocardiogram 79 (78.2) 101 47 (77.0) 61 32 (80.0) 40
Pulmonary HT 17 (22.1) 77 12 (26.1) 46 5 (16.1) 31
Pulmonary Function Test 28 (26.7) 105 2 (3.1) 65 26 (65.0) 40
 Infant pulmonary function test 2 (1.9) 102 2 (3.2) 63 - -
Sleep Study 44 (64.7) 68 31 (65.9) 47 1 2 (60.0) 20
BAL 54 (65) 83 27 (57.4) 47 26 (74.3) 35
GORD 10 (10.2) 98 5 (7.6) 66 5 (15.6) 32
Genetics Investigations 25 (25.0) 100 21 (33.3) 63 4 (10.8) 37
Histological Second Opinion Sought 30 (49.2) 61 19 (50) 38 11 (47.8) 23
  1. BAL Bronchoalveolar lavage; GORD Gastro-oesophageal reflux disease; CT Computed tomography; HT, Hypertension
  2. a Age at diagnosis was not documented for 1 subject