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Fig. 3 | Orphanet Journal of Rare Diseases

Fig. 3

From: Minimal clinically important difference for the 6-min walk test: literature review and application to Morquio A syndrome

Fig. 3

Absolute six-minute walk test (6MWT) minimal clinically important difference (MCID) using anchor-based methods. Sources: 1 & 2 = du Bois, 2010 [29] and du Bois, 2011 [30]; 3 = Swigris, 2010 [31]; 4 = Holland, 2009 [42]; 5 = Holland, 2010 [43]; 6 = Polkey, 2013 [32]; 8 = Puhan, 2011 [44]; 9 = Redelmeier, 1997 [45]; 11 = Lee, 2014 [46]; 12 & 13 = Gremeaux, 2011 [47] and Gremeaux, 2011 [48]; 15 = Mathai, 2012 [49]; 16 = Henricson, 2013 [28]; 18 = Kwok, 2013 [50]. The green, red, blue, and orange bars represent studies conducted in patients with respiratory, cardiovascular, muscular, and ‘other’ (i.e., frail elderly) diseases, respectively. CAD: coronary artery disease; COPD: chronic obstructive pulmonary disease; IPF: idiopathic pulmonary fibrosis; PAH: pulmonary arterial hypertension

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