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Table 3 Estimated prevalence of GO and variants of GO. (a) shows prevalence by severity and (b) for clinical variants (all grades of severity)

From: Graves’ orbitopathy as a rare disease in Europe: a European Group on Graves’ Orbitopathy (EUGOGO) position statement

 

PREVALENCE (per 10,000 population)

PROPORTION OF PATIENTS WITH VARIANT

SOURCE

(a)

 All cases of GO

8.97

-

[18]

15.48

 

[19, 20]

 Mild GO

5.83

65.0%

[18]

11.03

72.8%

[19, 20]

 Moderate-to-severe

2.96–4.45

33.0–29.4%

[1820]

 Sight-threatening

0.18

2.0%

[11, 14]

(b)

 Euthyroid/hypothyroid GO

0.02–1.10

0.2–11.0%

[2933]

 GO associated with dermopathy

0.15

1.5%

[7]

 GO associated with acropachy

0.03

0.3%

[7]

 Asymmetrical GO

1.00–5.00

10.0–50.0%

[3436]

 Unilateral GO

0.50–1.50

5.0–15.0%

[3538]