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Table 3 Estimated prevalence of GO and variants of GO. (a) shows prevalence by severity and (b) for clinical variants (all grades of severity)

From: Graves’ orbitopathy as a rare disease in Europe: a European Group on Graves’ Orbitopathy (EUGOGO) position statement

  PREVALENCE (per 10,000 population) PROPORTION OF PATIENTS WITH VARIANT SOURCE
(a)
 All cases of GO 8.97 - [18]
15.48   [19, 20]
 Mild GO 5.83 65.0% [18]
11.03 72.8% [19, 20]
 Moderate-to-severe 2.96–4.45 33.0–29.4% [1820]
 Sight-threatening 0.18 2.0% [11, 14]
(b)
 Euthyroid/hypothyroid GO 0.02–1.10 0.2–11.0% [2933]
 GO associated with dermopathy 0.15 1.5% [7]
 GO associated with acropachy 0.03 0.3% [7]
 Asymmetrical GO 1.00–5.00 10.0–50.0% [3436]
 Unilateral GO 0.50–1.50 5.0–15.0% [3538]